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ANTITHROMBOTIC EFFECT OF ESCALATING DOSES OF PEG HIRUDIN IN HUMANS

ANTITHROMBOTIC EFFECT OF ESCALATING DOSES OF PEG HIRUDIN IN HUMANS
聚乙二醇水蛭素剂量递增对人体的抗血栓作用
批准号：
6246281
负责人：
JAMES H CHESEBRO
金额：
$4.47万
依托单位：
MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-03-12 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6246281
关键词：
cardiovascular disorder chemotherapy cardiovascular pharmacology clinical research coronary disorder dosage drug screening /evaluation hirudins human subject human therapy evaluation intravenous administration platelets thrombosis

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中文摘要
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英文摘要
The main aim of this proposal is to test the dose-antithrombotic response of escalating doses of intravenous hirudin in patients with chronic coronary or peripheral arterial disease. This aim will be tested by infusing escalating doses of intravenous PEG-hirudin and performing ex vivo perfusion studies of platelet-thrombus formation using blood from the antecubital vein of the patients.
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CLOPIDOGREL DOSING IN HUMAN ARTERIAL THROMBUS FORMATION
CLOPIDOGREL DOSING IN HUMAN ARTERIAL THROMBUS FORMATION
ANTITHROMBOTIC EFFECT OF ESCALATING DOSES OF PEG HIRUDIN IN HUMANS
LIPID LOWERING WITH SIMVASTATINE AFTER ACURE CORONARY SYNDROMES
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