GENETICS OF ASTHMA (CSGAII)

哮喘遗传学 (CSGAII)

• 批准号: 6264855
• 负责人: MALCOLM N BLUMENTHAL
• 金额: $ 4.48万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6264855
• 关键词: asthma; clinical research; family genetics; gene environment interaction; gene expression; genetic mapping; human subject

Asthma is a chronic inflammatory disease of the airways. In the United States, asthma affects 14 to 15 million people. It is the most common chronic disease of childhood, affecting an estimated 4.8 million children. More than 5,000 people die of asthma annually. Both sexes and all racial groups are affected. Aim: to identify the location of the gene which causes asthma. Our secondary aim is to clearly define asthma by identifying the genetic components of this disease, as well as the environmental component (including allergies, age, and gender).

哮喘是一种慢性气道炎症性疾病。 在美国，哮喘影响着1400万至1500万人。 它是儿童最常见的慢性疾病，估计影响480万儿童。每年有5,000多人死于哮喘。 男女和所有种族群体都受到影响。 目的：确定导致哮喘的基因的位置。 我们的第二个目标是通过识别这种疾病的遗传成分以及环境成分（包括过敏，年龄和性别）来明确定义哮喘。