CRYSTAL STRUCTURE OF CATALYTIC CORE FRAGMENT OF ROUS SARCOMA VIRUS INTEGRASE

我们已经收集了关于植酸蛋白酶（phytepsin）（在大肠杆菌中1483个氨基酸res. 对称 单位，大麦天冬氨酸蛋白酶）， 10-甲酰基四氢叶酸酶（FDH）的N末端结构域，（620 Res. 在亚述。 单位）在3.0 A再溶解和MAD数据在N-端 STAT 4结构域（assym. 通过使用这些数据，我们 解决了植物蛋白酶的结构，现在最后的精制是在 中求进工作总 外佣的结构还没有解决。 STAT 4 MAD数据 被证明是无用的，因为φ轴滑动到2度。 期间 数据收集的同时我们使用光束反转。 的问题 Phi轴已经报告给国际象棋工程师，据我所知，现在， 已经修好了。

We have collected data on phytepsin (1483 amino acid res. in assym. unit, barley aspartic protease) at 2.3 A resolution, N-terminal domain of 10-formyltetrahydrofolate enzyme (FDH), ( 620 res. in assym. unit) at 3.0 A re-solution and MAD data on N-terminal domain of STAT4 (496 res. in assym. unit) By using these data we solved structure of phytepsin and now the final refine-ment is in progress. FDH structure has not been solved yet. STAT4 MAD data proved to be useless, since Phi axes was slipping up to 2 deg. during data collection while we were using beam inversion. The problem with the Phi axes had been reported to CHESS engineers, and as I know, now it has been fixed.