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CRYSTAL STRUCTURE OF CATALYTIC CORE FRAGMENT OF ROUS SARCOMA VIRUS INTEGRASE

CRYSTAL STRUCTURE OF CATALYTIC CORE FRAGMENT OF ROUS SARCOMA VIRUS INTEGRASE
劳斯肉瘤病毒整合酶催化核心片段的晶体结构
批准号:
6281319
负责人:
ALEXANDER WLODAWER
金额:
$1.84万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-09-15 至 1999-08-14

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中文摘要
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英文摘要
We have collected data on phytepsin (1483 amino acid res. in assym. unit, barley aspartic protease) at 2.3 A resolution, N-terminal domain of 10-formyltetrahydrofolate enzyme (FDH), ( 620 res. in assym. unit) at 3.0 A re-solution and MAD data on N-terminal domain of STAT4 (496 res. in assym. unit) By using these data we solved structure of phytepsin and now the final refine-ment is in progress. FDH structure has not been solved yet. STAT4 MAD data proved to be useless, since Phi axes was slipping up to 2 deg. during data collection while we were using beam inversion. The problem with the Phi axes had been reported to CHESS engineers, and as I know, now it has been fixed.
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CRYSTAL STRUCTURE OF STAT4 N TERMINAL DOMAIN
  • 批准号:
    6667832
  • 项目类别:
  • 资助金额:
    $14.27万
  • 财政年份:
    2002
  • 负责人:
    ALEXANDER WLODAWER
  • 依托单位:
CRYSTAL STRUCTURE OF STAT4 N TERMINAL DOMAIN
  • 批准号:
    6491155
  • 项目类别:
  • 资助金额:
    $14.27万
  • 财政年份:
    2001
  • 负责人:
    ALEXANDER WLODAWER
  • 依托单位:
CRYSTAL STRUCTURE OF STAT4 N TERMINAL DOMAIN
  • 批准号:
    6339167
  • 项目类别:
  • 资助金额:
    $1.38万
  • 财政年份:
    2000
  • 负责人:
    ALEXANDER WLODAWER
  • 依托单位:
STRUCTURAL STUDIES OF FIV PROTEASE INHIBITOR COMPLEXES
  • 批准号:
    6340974
  • 项目类别:
  • 资助金额:
    $11.38万
  • 财政年份:
    2000
  • 负责人:
    ALEXANDER WLODAWER
  • 依托单位:
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