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EPR TITRATION OF MUA TRANSPOSASE W/ MN(II)

EPR TITRATION OF MUA TRANSPOSASE W/ MN(II)
EPR 滴定 MUA 转座酶 W/ MN(II)
批准号：
6121161
负责人：
TANIA A BAKER
金额：
$0.39万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-05-05 至 2000-04-30
来源：
https://reporter.nih.gov/project-details/6121161
关键词：
bioengineering /biomedical engineering biological products biomaterials biomedical equipment development biomedical resource technology /technique

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英文摘要
EPR and resonance Raman differences are seen with Fe3+BLM poly d(CG) as compared to poly d(AT). Multiple conformers of the Fe3+ BLM are seen in buffer and when the drug binds poly d(AT). Narrowing of features of the EPR absorption derivative upon binding to d(CG) or to DNA speak for specific interaction, as demonstrated by resonance Raman. A model is presented suggesting that drug recognition of CG sites entails the formation of a specific hydrogen bond from the amino pyrimidine of BLM to a base d(CG). A paper has been written and submitted describing this work.
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Macromolecular interactions controlling the ALA synthases, keystone enzymes that initiate heme biosynthesis
Macromolecular interactions controlling the ALA synthases, keystone enzymes that initiate heme biosynthesis
BASIS OF SUBSTRATE SELECTION BY BACTERIAL ADAPTOR PROTEINS
  • 批准号：
    8169213
  • 项目类别：
  • 资助金额：
    $1.4万
  • 财政年份：
    2010
  • 负责人：
    TANIA A BAKER
  • 依托单位：
    CORNELL UNIVERSITY
ADAPTOR-PROTEIN MEDIATED RECOGNITION AND REGULATION OF PROTEIN DEGRADATION
  • 批准号：
    7955083
  • 项目类别：
  • 资助金额：
    $0.33万
  • 财政年份：
    2009
  • 负责人：
    TANIA A BAKER
  • 依托单位：
    CORNELL UNIVERSITY
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