LOSIGAMONE AS MONOTHERAPY IN TREATMENT OF COMPLEX PARTIAL SEIZURES

与美国国立卫生研究院癫痫科和其他12个临床中心合作的综合癫痫项目将提供90名已完成患者的数据。综合癫痫项目将通过目前该项目使用的计算机化癫痫患者日志来识别候选人。进一步确定这项为期21个月的试验的潜在候选人预计将来自3名医生，1名咨询医生和2名药剂师，其中一名执行特定的患者任务。两名护士协调员，一名作为后备和一名数据输入协调员将完成研究小组。GCRC将进一步管理患者随访和静脉切开术服务，并提供住院和门诊就诊。为了满足患者的最佳给药需求，需要住院过夜。在7个月的注册期内，需要进行两次过夜访问。

The comprehensive epilepsy program in conjunction with the Epilepsy Branch of NIH and 12 other clinical centers will provide data on 90 completed patients. The Comprehensive Epilepsy program will identify candidates tracked by the computerized epilepsy patient log currently utilized by the program. Further identification of potential candidates for this 21 month trial is expected to come from 3 physicians, 1 consulting physician, and 2 pharmacists with one performing specific patient tasks. Two nurse coordinators with on acting as backup and a data entry coordinator will complete the research team. Further management of patient follow-up and phlebotomy services will be performed by the GCRC with provisions for inpatient and outpatient visits. Overnight hospitalization is required for titration to meet the patient's optimal dosing needs. An overnight visit is required twice throughout the seven month enrollment period.