AUTOMATED PROTEIN SEQUENCER PURCHASE

此应用程序请求支持购买Perkin Elmer/应用生物系统事业部492型自动蛋白质 取代过时的蛋白质测序仪的测序仪 由鲍曼·格雷的蛋白质分析核心实验室运营 维克森林大学医学院。现存的蛋白质 Sequencer已经14岁了，已经过时了，因为专业 维修所需的部件不再可用。十二个人的小组 NIH资助的调查人员得到了NIH总共14笔赠款的支持 四个不同的研究所构成了主要的用户群体。每一个 主要用户需要高灵敏度的蛋白质序列分析 他们的NIH研究项目的进展方法。建议的新 仪器将作为共享资源运行，该资源可在 向维克森林的所有调查人员收取服务费 大学。这个实验室由马克·莱弗利博士领导，他 已经管理了14年的旧蛋白质测序仪的操作 好几年了。莱弗利博士拥有理想的技术专长和经验 操作新仪器，并根据需要应用其功能 用户的数量。这台新仪器将使实验室能够 继续提供蛋白质序列分析服务，并将 通过提供更高的能力来增强实验室的能力 对氨基酸序列的灵敏检测和更高的容量。 拟议文书改进后的能力将增强 取得进展并扩大对美国国立卫生研究院资助的 它的用户。鲍曼·格雷医学院致力于 长期支持该设备的使用和维护 乐器。

This application requests support for the purchase of a Perkin Elmer/Applied Biosystems Division Model 492 automated protein sequencer to replace an outdated and obsolete protein sequencer operated by the Protein Analysis Core Laboratory of the Bowman Gray School of Medicine of Wake Forest University. The existing protein sequencer is 14 years old and has become obsolete because major components for its repair are no longer available. A group of twelve NIH funded investigators supported by a total of 14 NIH grants from four different institutes constitutes the major user group. Each of the major users requires high sensitivity protein sequence analysis methods for progress on their NIH research projects. The proposed new instrument will be operated as a shared resource that is available on a fee-for-service basis to all investigators at Wake Forest University. This laboratory has been directed by Dr. Mark Lively who has managed the operation of the older protein sequencer for 14 years. Dr. Lively has ideal technical expertise and experience to operate the new instrument and to apply its capabilities to the needs of the users. The new instrument will enable the laboratory to continue to provide protein sequence analysis services and will enhance the capabilities of the laboratory by providing higher sensitivity detection of amino acid sequences and increased capacity. The improved capabilities of the proposed instrument will enhance progress and expand the scope of research on the NIH-funded grants of its users. The Bowman Gray School of Medicine is committed to the long term support of the utilization and maintenance of this instrument.