课题基金 / 基金详情

PLACEBO-CONTROLLED SAFETY AND EFFICACY STUDY OF AMINOGUANIDINE IN DIABETES

PLACEBO-CONTROLLED SAFETY AND EFFICACY STUDY OF AMINOGUANIDINE IN DIABETES
氨基胍治疗糖尿病的安慰剂对照安全性和有效性研究
批准号：
6245661
负责人：
TREVOR J. ORCHARD
金额：
$1.76万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-03-18 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6245661
关键词：
aminoguanidine blood chemistry chemoprevention clinical research crosslink diabetes mellitus therapy diabetic nephropathy drug adverse effect drug screening /evaluation glycation human subject human therapy evaluation insulin dependent diabetes mellitus kidney disorder chemotherapy kidney function pharmacokinetics urinalysis

项目摘要

项目成果

TREVOR J. ORCHARD的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The primary objective of this trial is to evaluate the safety & efficacy of aminoguanidine in preserving renal function in patients with insulin dependent diabetes mellitus & overt diabetic nephropathy. Secondary; 1)to evaluate the effect of aminoguanidine on protein crosslinking in diabetic pts as measured by circulating blood and urinary concentrations of advanced glycated endproducts (AGEs),2) to evaluate the relationship between plasma aminoguanidine concentrations and primary and secondary efficacy endpoints as well as adverse events
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Health system based clinical trial recruitment
Evaluation of Differing Type 1 Diabetes Regimens in Youth in the Developing World
Epidemiology of Diabetes Complications (EDC) Phase II: renewal
Cardiovascular Epidemiology Training Program
海外基金