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EFFECT OF KHCO3 ON RATE OF BONE MASS DECLINE IN PRE AND POSTMENOPAUSAL WOMEN

EFFECT OF KHCO3 ON RATE OF BONE MASS DECLINE IN PRE AND POSTMENOPAUSAL WOMEN
KHCO3 对绝经前和绝经后妇女骨量下降率的影响
批准号：
6246386
负责人：
ANTHONY SEBASTIAN
金额：
$4.89万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-04 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6246386
关键词：
bicarbonates biopsy bone density chemoprevention clinical research drug screening /evaluation female human subject longitudinal human study menstrual cycle osteoporosis postmenopause potassium

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英文摘要
This study is to compare KHCO3 and placebo in attenuating or preventing age-related bone mass decline in postmenopausal women. Percutaneous iliac crest bone biopsies will be done in women who have been taking KHCO3 or placebo for 2 yrs. This is to determine if the new bone being formed duriing KHCO3 administration is histologically normal. This is a cooperative study between our GCRC and the GCRC at UCLA. Bone biopsy specimens will be processed by the CORE lab and sent to UCLA CORE Lab for analysis.
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