Discovery and validation of novel biomarkers of drug response in metastatic colon cancer.

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Colorectal cancer is the third leading cause of cancer related death in Australia. While there are now a number of treatment options for patients with colon cancer, there is significant variability in response among patients to individual drugs. This NHMRC project grant will seek to identify genetic markers which predict the likelihood of a patient responding to a specific therapy. This will enable individual patients to be treated with the drug most likely to be of benefit to them.