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ROLE OF UV INDUCED CYTOKINES AND GROWTH FACTORS IN THE PATHOGENESIS OF PTERYGIUM

ROLE OF UV INDUCED CYTOKINES AND GROWTH FACTORS IN THE PATHOGENESIS OF PTERYGIUM
紫外线诱导的细胞因子和生长因子在翼状胬肉发病机制中的作用
批准号:
6268411
负责人:
JOHN C ANSEL
金额:
$6.18万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-03-01 至 1999-04-30

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中文摘要
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英文摘要
Chronic UV exposure to the eye has been linked to the development of pterygium. However, the pathogenesis of this effect is unclear. We propose that UV may trigger this vascular hyperproliferative lesion by the induction of conjunctival and corneal cytokines and growth factors that result in overgrowth of the conjunctiva into the cornea. Specific Aims: 1: To determine the effect of UV on specific corneal and conjunctival epithelial cell cytokines and growth factors. 2: To examine the production of specific cytokines and growth factors in human pterygium tissue.
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Keratinocyte TLR in Cutaneous Immunity
  • 批准号:
    7479320
  • 项目类别:
  • 资助金额:
    $27.38万
  • 财政年份:
    2006
  • 负责人:
    JOHN C ANSEL
  • 依托单位:
Keratinocyte TLR in Cutaneous Immunity
  • 批准号:
    7269366
  • 项目类别:
  • 资助金额:
    $27.77万
  • 财政年份:
    2006
  • 负责人:
    JOHN C ANSEL
  • 依托单位:
Keratinocyte TLR in Cutaneous Immunity
  • 批准号:
    7150977
  • 项目类别:
  • 资助金额:
    $32.97万
  • 财政年份:
    2006
  • 负责人:
    JOHN C ANSEL
  • 依托单位:
PROTEINASE ACTIVATED RECEPTORS IN CORNEAL INFLAMMATION
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