Dissecting the role of insulin-regulated phosphorylation of Rab guanine nucleotide exchange factors in GLUT4 trafficking
Dissecting the role of insulin-regulated phosphorylation of Rab guanine nucleotide exchange factors in GLUT4 trafficking
批准号:
nhmrc : 1047067
负责人:
Dr Jacqueline Stoeckli
金额:
$41.91万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
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英文摘要
Diabetes and obesity are epidemic in the developed world. Impaired insulin action is a major cause. A key contributor is reduced glucose uptake into muscle and fat driving the pancreas to overproduce insulin. We have recently discovered three new molecules that we believe hold the secret to how insulin regulates the removal of the glucose from the blood stream after a meal. This proposal focuses on these three molecules and their regulation.
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批准号:nhmrc : GNT1120201
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项目类别:Project Grants
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资助金额:$118.32万
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财政年份:2017
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负责人:Dr Jacqueline Stoeckli
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依托单位:
Dissecting Rapamycin sensitive and insensitive effects of mTOR
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依托单位:
Functional analysis of the Rab GAP AS160
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依托单位:
The role of Rab GTPases and Rab GTPase activating proteins in Insulin Action
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批准号:nhmrc : 535923
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项目类别:NHMRC Project Grants
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资助金额:$50.79万
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财政年份:2009
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负责人:Dr Jacqueline Stoeckli
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项目类别:面上项目
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批准年份:2023
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依托单位: