ACTG 076--ORAL ZIDOVUDINE IN PREGNANT HIV INFECTED WOMEN AND THEIR CHILDREN

ACTG 076--艾滋病毒感染孕妇及其子女口服齐多夫定

• 批准号: 6274453
• 负责人: Stuart E Starr
• 金额: $ 2.5万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-15 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6274453
• 关键词: AIDS therapy; HIV infections; chemoprevention; clinical research; embryo /fetus chemotherapy; female; human pregnant subject; human therapy evaluation; infant human (0-1 year); oral administration; outcomes research; pregnancy disorder chemotherapy; vertical transmission; women's health; zidovudine

To determine whether the vertical HIV transmission rate from mother to infant can be reduced by continuous oral ZDV admin. to HIV infected pregnant women begining at 14 weks gestation with an intrapartum intravenous dose, and oral ZDV admin. to their newborn infants from birth to six weeks of age.

为了确定艾滋病毒从母亲到母亲的垂直传播率， 婴儿可以通过连续口服ZDV给药来减少。艾滋病毒感染者 妊娠14周开始的孕妇， 静脉内给药和口服ZDV给药。给他们的新生儿， 出生到六周大。