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PRESERVING OVARIAN FUNCTION IN LUPUS NEPHRITIS

PRESERVING OVARIAN FUNCTION IN LUPUS NEPHRITIS
狼疮性肾炎患者的卵巢功能保护
批准号：
6275028
负责人：
MARY ANNE. DOOLEY
金额：
$1.58万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6275028
关键词：
adolescence (12-20) chemoprevention clinical research clinical trials connective tissue disorder chemotherapy cyclophosphamide drug adverse effect drug screening /evaluation egg /ovum female gonadotropin releasing factor human subject human therapy evaluation nephritis ovary placebos stimulant /agonist systemic lupus erythematosus young adult human (21-34)

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中文摘要
翻译
这项研究将是一项随机、双盲的安慰剂试验，共有50名 年龄在13至45岁之间的女性。预计路普隆 将由该公司提供。这项研究的目的是为了 使用一种名为Lupron的药物，它是一种释放促性腺激素的药物 激素激动剂。这种药物可以有效地关闭卵巢功能。 下丘脑的脑下垂体水平。理论是，如果在 给环磷酰胺的时间，卵巢功能已经关闭 下了蛋就得救了。
英文摘要
This study will be a randomized, double blind placebo trial, with 50 women between the ages of 13 and 45. It is anticipated that the lupron will be supplied by the company. The purpose of this study is to look at the use of a drug called lupron which is a gonadotropin releasing hormone agonist. This drug effectively shuts down ovarian function at the hypothalamic pituitary level. The theory being, that if during the time of cyclophosphamide administration, ovarian function has been shut down the eggs will be saved.
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