NITROGEN BALANCE AND AMINO ACID CLEARANCE IN PEDIATRIC PATIENTS WITH ARF ON CRRT

CRRT 上 ARF 儿科患者的氮平衡和氨基酸清除率

• 批准号: 6274719
• 负责人: TIMOTHY E BUNCHMAN
• 金额: $ 2.15万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6274719
• 关键词: acute renal failure; aminoacid metabolism; child (0-11); clearance rate; clinical research; clinical trials; diet therapy; dietary proteins; dosage forms; human subject; human therapy evaluation; nitrogen balance; nutrient intake activity; nutrition related tag; parenteral feedings; pediatrics; tube feeding

Meeting nutritional needs in critically ill patients is a primary concern in their management and recovery. Nitrogen balance for these patients by adequate protein intake through enteral/parenteral nutrition is a key aim. How much Nitrogen intake and the Amino Acid (AA) composition fo this protein in patients with acute renal failure (ARF) is not clearly established. Adjustments in the protein intake of the patient for the form of RRT (renal replacement therapy) is often necessary. An increasingly common form of RRT in ARF is Continuous Venovenous Hemofiltration (CVVH). Two forms are commonly used: CVVH with FRF (filtered renal failure) and CVVHD (continuous venovenous diafiltration). This project's objective will be to evaluate pediatric patients on CRRT for Amino Acid Clearance by both modalities (CCVH + FRF vs. CVVHD) to determine its effect on nitrogen balance.

满足危重病人的营养需求是首要任务