BROMODEOXYURIDINE AND RADIATION FOR CANCER OF LIVER AND/OR BILE DUCTS

溴脱氧尿苷和放射治疗肝癌和/或胆管癌

• 批准号: 6274628
• 负责人: JOHN M ROBERTSON
• 金额: $ 2.15万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6274628
• 关键词: biliary tract neoplasm; bromodeoxyuridine; clinical research; clinical trials; combination cancer therapy; human subject; human therapy evaluation; liver neoplasms; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy

Liver cancers occur frequently and are a major source of morbidity and mortality. More effective treatment methods would provide significant palliation for many patients and possibly cure some of the few patients with cancer totally confined to the liver. This investigational study combines the most technologically advanced radiotherapy with direct administration of a potent radiosensitizer in the treatment of liver cancer. The approach taken is based upon extensive prior preclinical and clinical studies funded as part of an ongoing Program Project Grant.

肝癌经常发生，是发病率的主要来源， mortality. 更有效的治疗方法将提供显著的 缓解了许多患者的病情，并可能治愈少数患者中的一些 癌症完全局限于肝脏。 这项调查性研究 将最先进的技术放射治疗与直接放射治疗相结合 在治疗肝脏疾病中施用有效的放射增敏剂 癌 所采用的方法是基于广泛的先前临床前 和临床研究作为正在进行的计划项目赠款的一部分。