BMY-42215-1（15-脱氧精胍菌素三盐酸盐）引起的急性肾移植排斥-猫眼课题宝

BMY-42215-1（15-脱氧精胍菌素三盐酸盐）引起的急性肾移植排斥

批准号：

2783402

负责人：

金额：

$2.28万

依托单位：

UNIVERSITY OF MICHIGAN AT ANN ARBOR

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/2783402

关键词：

clinical research combination chemotherapy corticosteroids drug screening /evaluation graft versus host disease guanidines human subject human therapy evaluation immunosuppressive intravenous administration kidney transplantation outcomes research transplant rejection

中文摘要

翻译

本研究旨在评估BMY-42215-1的有效性和安全性

英文摘要

This study is designed to assess the efficacy and safety of BMY-42215-1 (deoxyspergualin, DSG) plus intravenous pulse corticosteroids compared with placebo plus intravenous pulse corticosteroids in the treatment of patients with acute renal allograft rejection episodes. The intent of the study is to establish whether the addition of 15-deoxyspergualin- trichloride to corticosteroids will improve the outcomes of rejection therapy and reduce the need for treatment with antilymphocyte agents such as OKT3 or ATGAM.

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会议论文

海外基金

ACUTE RENAL GRAFT REJECTION W/ BMY-42215-1 (15-DEOXYSPERGUALIN TRIHYDROCHLORIDE)

项目摘要

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