课题基金 / 基金详情

D XYLOSE AND PREDNISONE ABSORPTION IN CHILDREN WITH HYPERSENSITIVITY

D XYLOSE AND PREDNISONE ABSORPTION IN CHILDREN WITH HYPERSENSITIVITY
过敏儿童对 D 木糖和泼尼松的吸收
批准号：
6275305
负责人：
LAUREN M. PACHMAN
金额：
$2.26万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6275305
关键词：
cardiovascular disorder chemotherapy child (0-11) clinical research gastrointestinal drug absorption human subject hypersensitivity intravenous administration methylprednisolone oral administration pediatric pharmacology pharmacokinetics vasculitis xylose

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英文摘要
1) To determine the pharmacokinetics of orally administered vs intravenous methylprednisolone in pediatric vasculitis (standardized at 50mg/M2). 2) To determine if impaired D-xylose absorption is correlated with markers of vasculitis (neopterin, vWfAg) and decreased absorption when oral drug is compared with IV drug. 3) To determine whether impaired D-xylose absorption improves with control of disease activity.
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