PREVALENCE AND PATTERN OF HEPATIC DYSFUNCTION FOLLOWING FONTAN PROCEDURE

Fontan 手术后肝功能障碍的患病率和模式

• 批准号: 6276175
• 负责人: MICHAEL R. NARKEWICZ
• 金额: $ 1.86万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6276175
• 关键词: clinical research; congenital heart disorder; hemodynamics; human subject; liver disorder; liver disorder diagnosis; liver function; noninvasive diagnosis; postoperative state

The Fontan procedure offers a means of palliating the hemogynamic derangements associated with some complex congenital heart lesions. The result, in most cases, is a chronically elevated systemic venous pressure. We propose to perform a battery of noninvasive tests of hepatic function in patients who have undergone the Fontan procedure in an attempt to define the prevalence and pattern of hepatic dysfunction (possible effect of systemic venous hypertension on the liver) in this population of patients.

Fontan手术提供了一种缓解血流动力学的方法 与一些复杂的先天性心脏病损有关的紊乱。 的 结果，在大多数情况下，是慢性升高的全身静脉 压力我们建议进行一系列非侵入性测试， 接受Fontan手术的患者的肝功能 试图定义肝功能障碍的患病率和模式 （全身静脉高压对肝脏的可能影响） 患者人群。