A MULTICENTER GROUP TO STUDY ACUTE LIVER FAILURE IN CHILDREN

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是收集儿童急性肝衰竭的前瞻性、人口统计和临床数据，这是一种因各种原因引起的罕见疾病，死亡率很高。 该机制将通过建立一个多中心研究小组来实现，该小组将美国各地至少 13 个中心的案例经验与德克萨斯大学西南分校的协调中心相结合。 将收集 7 天的数据和血清以供将来研究冷冻。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to gather prospective, demographic and clinical data on acute liver failure in childhood, an infrequent condition of varying causes, which carries a high mortality. The mechanism will be through the development of a multi-centered study group combining the case experience of at least 13 centers from around the United States, with the coordinating center at the University of Texas, Southwestern. Data and serum to be frozen for future studies will be collected for 7 days.