A MULTICENTER GROUP TO STUDY ACUTE LIVER FAILURE IN CHILDREN

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，不一定是研究者的机构。 本研究的目的是收集儿童急性肝衰竭的前瞻性、人口统计学和临床数据，急性肝衰竭是一种罕见的不同原因的疾病，死亡率很高。 该机制将通过建立一个多中心研究小组，将美国各地至少13个中心的案例经验与德克萨斯大学西南分校的协调中心结合起来。 将收集7天的数据和血清，以冷冻用于未来研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to gather prospective, demographic and clinical data on acute liver failure in childhood, an infrequent condition of varying causes, which carries a high mortality. The mechanism will be through the development of a multi-centered study group combining the case experience of at least 13 centers from around the United States, with the coordinating center at the University of Texas, Southwestern. Data and serum to be frozen for future studies will be collected for 7 days.