DETERMINATION OF EXCITATION ORDER OF MULTIPHOTON PHOTODAMAGE

我们一直在评估为我们的行动收集的数据 DNA合成抑制率的光谱测定 阶数n，使用一般的剂量-效应方程，其中S是 归一化生存和剂量D定义为Int。( 辐照度i以光子为单位/S(m2，n为光子数 单次激励事件或激励顺序所必需的。) 初步分析表明，观察到的损坏是由 不同波长的不同吸收物质--700 nm 损伤似乎来自单光子事件，在740 nm处看起来 来自双光子事件。进一步的研究正在进行中，以证实 这一观察结果。

We have been evaluating the data we have collected for our action spectrum of DNA synthesis inhibition to determine the excitation order, n, using the general dose-response equation, , where S is the normalized survival and the dose, D, is defined as Int. (The irradiance, I, is in photons/s((m2, and n is the number of photons required for a single excitation event, or the excitation order.) Preliminary analysis suggests that the observed damage is arising from different absorbing species at different wavelengths -- at 700 nm damage appears to be from one-photon events and at 740 nm it appears to be from two-photon events. Further studies are underway to confirm this observation.