CHARACTERIZATION OF RAT HEMOGLOBIN THIYL RADICALS BY W BAND

通过 W 波段表征大鼠血红蛋白硫酰基自由基

• 批准号: 6120646
• 负责人: RONALD P MASON
• 金额: $ 0.54万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-15 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6120646
• 关键词: animal tissue; biomedical equipment development; biomedical resource

High frequency (W-band, 95 GHz) EPR spectroscopy was applied in order to determine very accurately the spectroscopic parameters (g and a-tensors) distinguishing the free radicals formed from rat hemoglobin by methemoglobin-generating agents and trapped by DMPO. The high resolving power of the W-band instrument makes it possible to recognize the signature of each different trapped free radical . Since preliminary results have been successful, we are now examining various DMPO spin adducts.

高频(W波段，95 GHz)EPR谱应用于 为了非常准确地确定光谱参数(g和 A-张量)区分大鼠血红蛋白形成的自由基 由高铁血红蛋白生成剂和DMPO捕获。高潮 W波段仪器的分辨率使其能够 识别每一种不同捕获的自由基的特征。 由于初步结果是成功的，我们现在正在研究 各种DMPO自旋加合物。