COMPLEXES INVOLVED IN RECEPTOR MEDIATED SIGNALING

参与受体介导信号转导的复合物

• 批准号: 6281352
• 负责人: Yi Liu
• 金额: $ 0.83万
• 依托单位: BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-01 至 1999-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281352
• 关键词: bacteria; biological products; biomedical resource; genetics; minerals; taste

In bacterial chemotaxis, t3W I membrane receptors are involved. These have N-terminal extracytoplasmic sensing domains connected by helices to C-terminal signaling domains in the cytoplasm. Receptor signaling involves regulation of a protein kinase, CheA. Kinase activation requires the formation of a higher order complex of 6-8 signaling domains per CheA. By EK these active complexes appear to be cylindrical bundles. STEM studies were initiated to try to deternime the stoichionietry of the components.

在细菌趋化过程中，t3wi膜受体参与其中。