COMPLEXES INVOLVED IN RECEPTOR MEDIATED SIGNALING

在细菌的趋化作用中，T3W I膜受体参与其中。 它们具有N-末端胞质外传感域，它们通过 细胞质中的螺旋到C末端的信号域。受体 信号转导涉及蛋白激酶CHEA的调节。激活剂 活化需要形成6-8的高阶络合物 每个CHEA的信令域。从EK来看，这些活性络合物似乎是 圆柱形束状物。茎的研究已经开始，试图确定 成分的化学计量学。

In bacterial chemotaxis, t3W I membrane receptors are involved. These have N-terminal extracytoplasmic sensing domains connected by helices to C-terminal signaling domains in the cytoplasm. Receptor signaling involves regulation of a protein kinase, CheA. Kinase activation requires the formation of a higher order complex of 6-8 signaling domains per CheA. By EK these active complexes appear to be cylindrical bundles. STEM studies were initiated to try to deternime the stoichionietry of the components.