VIBRATIONAL SPECTROSCOPIC STUDY OF LABELED DNA OLIGOMERS: HIV

标记 DNA 低聚物的振动光谱研究：HIV

• 批准号: 6281460
• 负责人: STEFAN FRANZEN
• 金额: $ 2万
• 依托单位: UNIVERSITY OF CALIF-LOS ALAMOS NAT LAB
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-01-15 至 1999-01-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281460
• 关键词: AIDS; bioengineering /biomedical engineering; biomaterials; biomedical equipment development; biomedical resource; immunology; infection; inflammation; lymphatic system; technology /technique; virus

The SIR provided [9- 15 Nl["N-amino]adenosine; 10mg [9- 1 ladenosine; 10mg adenosine; 10mg (CAG)6; 5mg The studies undertaken here are bioanalytical studies of the feasibility of detection of vibrational mode frequency shifts in a single isotopically labeled base in a large oligomeric DNA molecule. The vibrational background due to water and the other vibrations of the oligomer serve as a background that makes difficult any interpretation of the vibrational spectrum. By specific isotopic labeling the ability to discern specific vibrational modes will be demonstrated.

SIR提供了[9-15 NL [“ N-Amino]腺苷； 10mg [9-1丁替氨酸； 10mg 腺苷； 10mg （CAG）6; 5mg这里进行的研究是对 检测振动模式频率转移的可行性 在大的寡聚DNA分子中的单同位素标记碱基。 由于水和其他振动引起的振动背景 低聚物用作使任何困难的背景 振动光谱的解释。 通过特定的同位素 标记识别特定振动模式的能力将是 证明。