Does pneumococcal vaccination protect against cardiovascular disease? A randomised placebo-controlled double blind trial

澳大利亚研究人员建立了一项新的多中心试验，以调查肺炎球菌疫苗在减少心脏病发作和中风方面的效果。来自澳大利亚6个地点的55岁至61岁的人将被邀请参加这项研究。被选中的参与者将在他们所在地区的一家诊所就诊，并将随机获得肺炎球菌疫苗或安慰剂疫苗。预计6000名参与者的结果将在4年后通过健康记录与政府数据库的链接来确定。

Australian researchers have set up a novel multi-centre trial to investigate the effects of the pneumococcal vaccination in reducing heart attacks and stroke. People aged 55 to 61 from 6 sites around Australia will be invited to participate in the study. The selected participants will attend a clinic in their area and will be randomly given the pneumococcal vaccine or a placebo vaccine. Outcomes on the expected 6000 participants will be ascertained by health record linkage with government databases after 4 years.