Australian Stroke Genetics Collaborative - Genome-wide association study in ischaemic stroke

澳大利亚中风遗传学合作组织 - 缺血性中风的全基因组关联研究

• 批准号: nhmrc : 569257
• 负责人: A/Pr Jonathan Sturm
• 金额: $ 76.08万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/australian-stroke-genetics-ischaemic-stroke/98886
• 关键词: Australian; Stroke; Genetics; Collaborative; Genome

The majority of stroke is caused by atherothrombosis, the formation of blood clots in brain blood vessels. Numerous genes are linked to atherothrombosis, but many studies examined genetic influences in isolation from environmental risk factors. We will examine the relevance of genetic variations linked to atherothrombosis, in the context of environmental risk factors. By determining the contribution of genetic and environmental factors in stroke, we will develop a stroke risk assessment tool.

大多数中风是由动脉粥样硬化血栓形成（脑血管中形成血栓）引起的。许多基因与动脉粥样硬化血栓形成有关，但许多研究将遗传影响与环境危险因素分开进行检查。我们将在环境风险因素的背景下研究与动脉粥样硬化血栓形成相关的遗传变异的相关性。通过确定遗传和环境因素对中风的影响，我们将开发中风风险评估工具。