Portable Noninvasive Acoustic Identification of Stroke

描述：（逐字引用申请人的摘要）有源信号 技术，与大学的大脑攻击团队合作， 马里兰州医疗中心，建议开发一种新型的便携式，非侵入性 系统将能够快速识别中风。约75万 每年都有人中风，其中80%以上是缺血性的。然而 只有1%的人接受TPA等药物治疗， 已知溶解凝块并促进有利结果， 发病3小时。在造成这种严重健康状况的众多原因中， 经济问题是不能快速区分缺血性和 出血性中风，以便进行干预。在第一阶段，小组将 研究中风患者的声学特征，以确定 可以进行区分。使用的设备将是一个修改后的版本， 由Active Signal开发的小型非侵入式声学系统， 在创伤患者身上做过测试确定的卒中识别假设 I期将在II期盲法试验中进行临床测试。最终目标 是开发一种EMS系统，以增加缺血性 中风患者将接受时间敏感的治疗。这将 大大减少残疾和医疗费用。 拟定商业应用： 不可用

DESCRIPTION: (Verbatim from the Applicant's Abstract) Active Signal Technologies, in partnership with the Brain Attack Team of the University of Maryland Medical Center, proposes to develop a novel portable, non-invasive system that will enable rapid identification of stroke. Approximately 750,000 people suffer a stroke each year and over 80 percent of these are ischemic. Yet only 1 percent of the entire number receive medical treatment such as TPA that is known to dissolve clots and promote favorable outcome if administered within 3 hours of onset. Among the many causes of this serious health and ultimately economic problem is the inability to rapidly differentiate ischemic from hemorrhagic strokes to allow intervention. During phase-I, the team will investigate acoustic signatures of persons with stroke to determine if this differentiation can be made. The device used will be a modified version of a small non-invasive acoustic system developed by Active Signal and successfully tested on trauma patients. Hypotheses for stroke identification determined in Phase I will be clinically tested in a Phase II blind trial. The ultimate goal is to develop a system for EMS units to increase the percentage of ischemic stroke patients who would receive time-sensitive therapies. This would significantly reduce disability and medical costs. PROPOSED COMMERCIAL APPLICATION: Not Available