Portable Noninvasive Acoustic Identification of Stroke

描述：(逐字摘自申请者摘要)激活信号 技术，与加州大学的大脑攻击团队合作 马里兰医疗中心提议开发一种新的便携式、非侵入性 该系统将能够快速识别中风。大约750,000 人们每年都会中风，其中超过80%是缺血性的。还没有 只有1%的人接受了TPA等医疗治疗， 已知如果在体内使用可以溶解血栓并促进良好的结果 发病3小时。在导致这种严重健康的众多原因中，最终 经济问题是无法快速区分缺血和 出血性中风，以便进行干预。在第一阶段，团队将 调查中风患者的声学特征，以确定这是否 可以进行区分。所使用的设备将是 基于有源信号的小型无创声学系统研制成功 在创伤患者身上进行了测试。中确定的卒中识别的假设 第一阶段将在第二阶段的盲法试验中进行临床测试。终极目标 是为急诊医疗单位开发一种系统，以增加缺血百分比 将接受时间敏感治疗的中风患者。这将会 显著降低残疾和医疗成本。 建议的商业应用： 不可用

DESCRIPTION: (Verbatim from the Applicant's Abstract) Active Signal Technologies, in partnership with the Brain Attack Team of the University of Maryland Medical Center, proposes to develop a novel portable, non-invasive system that will enable rapid identification of stroke. Approximately 750,000 people suffer a stroke each year and over 80 percent of these are ischemic. Yet only 1 percent of the entire number receive medical treatment such as TPA that is known to dissolve clots and promote favorable outcome if administered within 3 hours of onset. Among the many causes of this serious health and ultimately economic problem is the inability to rapidly differentiate ischemic from hemorrhagic strokes to allow intervention. During phase-I, the team will investigate acoustic signatures of persons with stroke to determine if this differentiation can be made. The device used will be a modified version of a small non-invasive acoustic system developed by Active Signal and successfully tested on trauma patients. Hypotheses for stroke identification determined in Phase I will be clinically tested in a Phase II blind trial. The ultimate goal is to develop a system for EMS units to increase the percentage of ischemic stroke patients who would receive time-sensitive therapies. This would significantly reduce disability and medical costs. PROPOSED COMMERCIAL APPLICATION: Not Available