Brain Trauma Assessment System

脑外伤评估系统

• 批准号: 6832929
• 负责人: JOHN Milton SEWELL
• 金额: $ 53.6万
• 依托单位: ACTIVE SIGNAL TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6832929
• 关键词: adolescence (12-20); adult human (21+); allied health personnel; bioengineering /biomedical engineering; biomedical equipment development; brain disorder diagnosis; brain injury; clinical biomedical equipment; clinical research; computer assisted diagnosis; computer system design /evaluation; diagnosis design /evaluation; diagnostic tests; early diagnosis; emergency care; field study; human subject; noninvasive diagnosis; patient monitoring device; patient oriented research; portable biomedical equipment; unconsciousness

Active Signal Technologies proposes to further develop and field-test its innovative hand-held Brain Trauma Assessment System (BTAS) with the objective of equipping EMS providers to directly measure brain pathology with sufficient sensitivity to confidently triage patients. With current field protocol, accurate diagnosis of traumatic brain injury (TBI) is difficult. BTAS through decreasing misdiagnosis will reduce unnecessary transports to trauma centers and will allow more timely, critical treatment of legitimate TBI's, hopefully diminishing death and serious injury from this significant came. Phase I demonstrated that, unlike the current Glasgow Coma Scale, a PDA-hosted, non-invasive, passive acoustic monitoring system can accurately distinguish early-stage TBI in patients with impaired consciousness from other non-threatening head insults and from alcohol and drug impairment. Active Signal aims to: 1) improve and simplify BTAS hardware for enabling access to a broader patient cross section, and 2) expand BTAS field evaluation from 15 to 150 patients with impaired consciousness, establishing the effectiveness of this assessment technique over a broad cross section of injury conditions in the very early stages of brain injury. The approach will include wireless sensors, push-button interface, increased monitoring stations, and a widely expanded field monitoring staff.

Active Signal Technologies建议进一步开发和现场测试其创新的手持式脑创伤评估系统（BTAS），目的是让EMS提供商能够直接测量脑病理学，并具有足够的灵敏度，以自信地对患者进行分流。目前的现场协议，准确诊断创伤性脑损伤（TBI）是困难的。BTAS通过减少误诊将减少不必要的运输到创伤中心，并将允许更及时，关键的治疗合法的TBI的，希望减少死亡和严重伤害，从这个重大的到来。第一阶段证明，与目前的格拉斯哥昏迷量表不同，PDA托管的非侵入性被动声学监测系统可以准确区分意识受损患者的早期TBI与其他非威胁性头部损伤以及酒精和药物损伤。Active Signal旨在：1）改进和简化BTAS 硬件，使访问更广泛的病人横截面，和2）扩大BTAS现场评估从15至150名患者意识受损，建立这种评估技术的有效性，在广泛的横截面的损伤条件在非常早期的脑损伤阶段。该方法将包括无线传感器、按钮接口、增加监测站和广泛扩大现场监测人员。