Safe environmental concentrations under uncertainty

不确定条件下的安全环境浓度

基本信息

  • 批准号:
    6337570
  • 负责人:
  • 金额:
    $ 9.99万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2001
  • 资助国家:
    美国
  • 起止时间:
    2001-09-30 至 2002-09-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (Verbatim from the Applicant's Abstract): The risk from an environmental contaminant is estimated with a risk equation involving the contaminant's concentration and other factors. Because the overall goal of risk management is to ensure such risks are not intolerably large, we need some way to backcalculate from constraints on risk mandated by regulation or prudence to the allowable environmental concentration for the contaminant. It is now well known that the approach used in deterministic assessments of simply inverting the risk equation to compute the cleanup goal does not work in a probabilistic assessmnent. Several approaches have been proposed, but none is sufficiently general. We have developed simple and efficient methods to compute cleanup goals that satisfy multiple simultaneous criteria in the context of a probabilistic assessment. The approach can be used with multiple receptors and with arbitrarily many constraints on percentiles of the target risk. The proposed research will explore the properties of this approach, conduct case studies to demonstrate its workability and extend it to more complex problems involving multiple effects (e.g., the toxicant causes two diseases), multiple trophic levels (e.g., plankton to shellfish to humans), and eventually to multiple exposure pathways (e.g., breathing, drinking, dermal absorption), and multiple potentially synergistic toxicants. PROPOSED COMMERCIAL APPLICATION: Commercialization would be in the from of a software library that could be used by software designers as well as end-users to compute the limits on concentrations of environmental contaminants that would yield tolerably low doses in humans under uncertainty and complex dynamics. The ability to compute such limits is needed by risk analysts in public health departments, potentially responsible" industries, and private consulting firms.
描述(逐字摘自申请人摘要):风险来自

项目成果

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SCOTT D FERSON其他文献

SCOTT D FERSON的其他文献

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{{ truncateString('SCOTT D FERSON', 18)}}的其他基金

Balancing Disclosure Risk with Inferential Power: Software for Intervalized Data
平衡披露风险与推理能力:间隔数据软件
  • 批准号:
    8517848
  • 财政年份:
    2012
  • 资助金额:
    $ 9.99万
  • 项目类别:
Balancing Disclosure Risk with Inferential Power: Software for Intervalized Data
平衡披露风险与推理能力:间隔数据软件
  • 批准号:
    8251091
  • 财政年份:
    2012
  • 资助金额:
    $ 9.99万
  • 项目类别:
Compensating for Uncertainty Biases in Health Risk Judgments
补偿健康风险判断中的不确定性偏差
  • 批准号:
    7926647
  • 财政年份:
    2010
  • 资助金额:
    $ 9.99万
  • 项目类别:
Safe environment concentrations under uncertainty
不确定性下的安全环境浓度
  • 批准号:
    6788050
  • 财政年份:
    2000
  • 资助金额:
    $ 9.99万
  • 项目类别:
Safe environment concentrations under uncertainty
不确定性下的安全环境浓度
  • 批准号:
    6645820
  • 财政年份:
    2000
  • 资助金额:
    $ 9.99万
  • 项目类别:
QUALITY ASSURANCE FOR ENVIRONMENTAL RISKS
环境风险的质量保证
  • 批准号:
    2896800
  • 财政年份:
    1996
  • 资助金额:
    $ 9.99万
  • 项目类别:
QUALITY ASSURANCE FOR ENVIRONMENTAL RISKS
环境风险的质量保证
  • 批准号:
    2864025
  • 财政年份:
    1996
  • 资助金额:
    $ 9.99万
  • 项目类别:
CONSERVATIVE RISK ANALYSIS USING DEPENDENCY BOUNDS
使用依赖性界限的保守风险分析
  • 批准号:
    2018482
  • 财政年份:
    1996
  • 资助金额:
    $ 9.99万
  • 项目类别:
DETECTING DISEASE CLUSTERS IN STRUCTURED ENVIRONMENTS
检测结构化环境中的疾病群
  • 批准号:
    2187080
  • 财政年份:
    1993
  • 资助金额:
    $ 9.99万
  • 项目类别:
DETECTING DISEASE CLUSTERS IN STRUCTURED ENVIRONMENTS
检测结构化环境中的疾病群
  • 批准号:
    2430476
  • 财政年份:
    1993
  • 资助金额:
    $ 9.99万
  • 项目类别:
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