Does pregnancy cause morphological changes in central as well as peripheral nerve pathways that control blood pressure?

怀孕会改变血压，但其机制尚不清楚。我们将使用最先进的解剖学方法来确定怀孕如何改变控制血压的神经。我们将识别神经细胞接收信息的变化，它们的形状以及它们与其他控制血压的神经细胞交流的方式。这些信息将有助于开发预防和治疗先兆子痫的新方法，先兆子痫是母亲及其新生儿死亡和残疾的主要原因。

Pregnancy changes blood pressure but the mechanism is unknown. We will use state-of-the-art anatomical methods to define how pregnancy alters nerves controlling blood pressure. We will identify changes in the information the nerve cells receive, in their shape and in the way they communicate with other blood pressure-controlling nerve cells. This information will help to develop new ways to prevent and treat pre-eclampsia, a major cause of death and disability for mothers and their newborns.