HIV Prevention Among Adolescent Women

描述(由申请人提供)：这项第一阶段可行性研究将 检查与HIV感染行为风险相关的心理社会因素 在青春期女性中。有关这些因素的数据将为制定 以计算机为基础的交互式干预，以降低艾滋病毒感染的风险 以及年轻女性中的艾滋病。在其6个月的过程中，第一阶段将 实现三个目标。首先，这项研究将评估行为流行病学 在48名黑人、拉丁裔和 白人青春期妇女，年龄在11岁到14岁之间，由六个人赞助 纽约市的社区网站。第二，我们将开发一个原型 互动软件版本，以降低艾滋病毒感染和艾滋病的风险 在那些年轻的女人中。第三，第一阶段将对原型软件进行试点测试 通过赞助对254名黑人、拉丁裔和白人年轻女性进行了调查 合作的纽约市社区网站。在一项随机设计中， 试点测试包括两个手臂的适度临床试验。网站上的年轻女性 被分配到计算机干预臂将与原型软件交互 在AIM 2开发。控制点的年轻女性将不会收到任何特殊的 干预。在电脑干预分娩前后，所有女孩都在 两个部门都将完成一系列结果衡量标准。通过实现其目标， 第一阶段将为第二阶段奠定基础，在第二阶段中，我们将全面开发 互动多媒体产品，帮助年轻女性降低感染艾滋病毒的风险 感染和艾滋病。第二阶段将包括一项随机临床试验，以测试 与来自不同社区的年轻女性一起开发的软件 大纽约市。如果第二阶段软件被证明是成功的，第三阶段将 将互动计划传播到学校和医疗保健机构，并 这样的社区机构参与了这个研发项目。 建议的商业应用：不可用

DESCRIPTION (provided by applicant): This Phase I feasibility study will examine psychosocial factors associated with behavioral risks for HIV infection among adolescent women. Data on those factors will inform the development of an interactive computer-based intervention to reduce the risks of HIV infection and AIDS among young women. Over the course of its 6 months, Phase I will accomplish three aims. First, the study will assess the behavioral epidemiology of risks for HIV infection and their reduction among 48 Black, Latina, and White adolescent women, aged 11 through 14 years, under the auspices of six community-based sites in New York City. Second, we will develop a prototype version of interactive software to reduce the risks of HIV infection and AIDS among those young women. Third, Phase I will pilot test the prototype software with a sample of 254 Black, Latina, and White young women through the auspices of the collaborating New York City community sites. In a randomized design, the pilot test involves a modest clinical trial with two arms. Young women in sites assigned to a computer intervention arm will interact with prototypic software developed in Aim 2. Young women in control sites will not receive any special intervention. Before and after computer intervention delivery, all girls in both arms will complete a battery of outcome measures. By meeting its aims, Phase I will lay a foundation for Phase II in which we will fully develop an interactive multimedia product to help young women reduce their risks for HIV infection and AIDS. Phase II will include a randomized clinical trial to test the developed software with young women from various community settings in greater New York City. If Phase II software proves successful, Phase III will disseminate the interactive program to schools and health care facilities and such community agencies as engaged in this R&D project. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE