HIV Prevention Among Adolescent Women

青春期妇女的艾滋病毒预防

• 批准号: 6696059
• 负责人: Jennifer Di Noia
• 金额: $ 49.01万
• 依托单位: INTERSYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-20 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6696059
• 关键词: AIDS education /prevention; African American; DVD /CD ROM; HIV infections; Hispanic Americans; adolescence (12-20); behavioral /social science research tag; caucasian American; clinical research; clinical trial phase III; computer program /software; computer system design /evaluation; disease /disorder proneness /risk; female; health behavior; human subject; psychometrics; racial /ethnic difference

DESCRIPTION (provided by applicant): This Phase II SBIR will develop and test a theory-based, culturally relevant, and age-appropriate intervention for HIV risk reduction among ethnic-racially diverse early adolescent females aged 11 through 14 years. Drawing from the theoretical and empirical literature and Phase I process and outcome data, Phase II will draft prevention content. Following review by a panel of community-based professionals and sample of 48 ethnic-racially diverse girls, the intervention will be revised and programmed for CD-ROM delivery. The efficacy of the CD-ROM-mediated intervention will be examined in a group-randomized trial. Girls will be recruited through youth services agencies in greater New York City. Following random assignment of sites to experimental and control study arms, 980 girls will complete pretest outcome measurement batteries. Experimental arm youths will interact with the software in six weekly on-site sessions. Youths in both study arms will complete posttest and six-month follow-up batteries. Outcome analyses will determine the efficacy of the computer-mediated intervention, relative to no intervention, in reducing girls' HIV risk behaviors and variables hypothesized to influence these behaviors. Should the CD-ROM intervention prove effective, it will be disseminated through direct marketing efforts and through licensing agreements with distributors of youth-oriented health promotion and disease prevention programs.

描述（由申请人提供）：该二期SBIR将开发和测试一种基于理论的、与文化相关的、适合年龄的干预措施，以降低11至14岁的不同种族的早期青春期女性的艾滋病毒风险。根据理论和经验文献以及第一阶段的过程和结果数据，第二阶段将起草预防内容。在社区专业人员小组和48名不同种族的女孩样本进行审查后，将对干预措施进行修订并编制CD-ROM分发方案。cd - rom介导干预的有效性将在一项组随机试验中进行检验。女孩将通过大纽约市的青年服务机构招募。在随机分配实验和控制研究组的地点后，980名女孩将完成测试前结果测量电池。参加实验的青少年将在六周的现场会议中与软件互动。两个研究组的青少年都将完成后测试和为期六个月的随访。结果分析将确定计算机干预相对于不干预在减少女孩艾滋病毒风险行为和假设影响这些行为的变量方面的功效。如果CD-ROM干预证明有效，将通过直接营销努力和通过与面向青年的健康促进和疾病预防方案的分销商签订许可协议进行传播。