GROWTH HORMONE VARIANTS, PULSATILITY & RESISTANT EXERCISE

本研究的目的是确定阻力训练对生长激素(GH)浓度、GH分泌的脉冲特征以及GH对靶组织的作用的影响。连续采血超过16小时，在正常情况下和大容量大强度耐力运动中测定GH浓度。假设生长激素会随着运动剂量的增加而增加，这是由于生长激素脉冲的宽度和幅度增加。GH免疫反应性有望表现出运动剂量关系，在较低分子量范围内预期反应最大。肌管的增殖也可能存在运动剂量关系。

The aim of this study is to determine the impact of resistance training on growth hormone (GH) concentrations, pulse characteristics of GH secretion and GH actions on target tissue. Serial blood sampling over 16 hours will be performed to measure GH concentrations under normal conditions and high volume heavy resistance exercise. It is hypothesized that GH will increase in response to the exercise dose, due to an increase in width and amplitude of GH pulses. GH immunoreactivity is expected to show an exercise -dose relationship where the greatest response is expected in the lower molecular weight range. It is also expected that there is an exercise-dose relationship on the proliferation of myotubes.