Double blind, randomised controlled trial assessing the efficacy of endothelin-1 receptor antagonism in preventing peri-procedural myonecrosis in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention

点击翻译按钮获取中文摘要

While the focus in the treatment of coronary artery disease has primarily been on the large vessels in the heart, vessels of small calibre may also play a significant role in patients with angina, heart attack, and muscle injury related to a stenting procedure.This project aims elucidate the possible mechanisms which cause dysfunction in these small vessels. I also hope to find a treatment strategy which may benefit patients with small vessel problems and thus improve their overall outcome.