SHORT-TERM EFFECTS OF AROMATASE INHIBITION ON BONE TURNOVER

芳香酶抑制对骨转换的短期影响

• 批准号: 6122766
• 负责人: CATHERINE MESSICK
• 金额: $ 3.88万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6122766
• 关键词: aromatase; bone metabolism; clinical research; human data; human old age (65+); human therapy evaluation; male; oxidoreductase inhibitor; skeletal pharmacology

Part of an University of Connecticut IRB approved, NIH funded study that involves the administration of an aromatase inhibitor (Arimidex) to men over the age of 65 to study the effect of estrogen ablation on hormone levels and markers of bone fromation and resorption. GCRC computers at Bowman Gray School of Medicine will be used in order to complete this study.

康涅狄格大学IRB批准的NIH资助的研究的一部分 涉及给男性使用芳香酶抑制剂(Arimidex) 65岁以上人群研究雌激素消融对激素的影响 骨形成和吸收的水平和标志物。GCRC计算机位于 鲍曼·格雷医学院将用来完成这项工作 学习。