Vesicle dynamics (invited resubmission)

囊泡动力学（邀请重新提交）

• 批准号: ST/I002979/1
• 负责人: Rory Duncan
• 金额: $ 1.76万
• 依托单位: Heriot-Watt University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=ST%2FI002979%2F1
• 关键词: Vesicle; dynamics; invited; resubmission

The programme will exploit techniques developed for use in astronomy but will apply them to measurements in live-cell biology. In particular, we will apply a technique developed to measure atmopherically-induced distortion of telescope images to the study of secretion processes in biology. Malfunction of these processes is poorly understood but contributes to about 9% of fatalities in the developed world, diabetes alone contributes to ~5% of deaths in the UK (British Heart Foundation Statistics). This project represents a collaboration between biologists, physicists and mathematicians and aims to monitor the dynamics of secretion with high precision. The study of these dynamics will improve our understanding of diseases such as epilepsy, diabetes, heart disease and asthma. This study will also allow us to assess the longer-term potential for applying astronomy-derived techniques for molecular biology research.

该计划将利用为天文学开发的技术，并将其应用于活细胞生物学的测量。特别是，我们将应用一种为测量大气引起的望远镜图像失真而开发的技术来研究生物学中的分泌过程。人们对这些过程的故障知之甚少，但在发达国家，这些过程的故障导致了约 9% 的死亡，仅糖尿病就导致了英国约 5% 的死亡（英国心脏基金会统计）。该项目代表了生物学家、物理学家和数学家之间的合作，旨在高精度监测分泌动态。对这些动态的研究将增进我们对癫痫、糖尿病、心脏病和哮喘等疾病的理解。这项研究还将使我们能够评估将天文学衍生技术应用于分子生物学研究的长期潜力。