AUTISM AS A COMPLEX INFORMATION PROCESSING DISORDER

许多神经行为模型已经被提出来解释 自闭症的临床表现。我们的研究审查 跨域的神经心理功能模式提供了 高阶能力同时受损的证据 跨域，在这些相同的域中完好无损的更简单的能力， 以及基本信息获取能力的完整性。 基于简单能力和复杂能力的分离 领域内和临床损害的优势在 对复杂信息需求最高的领域 经过处理，我们提出自闭症是 复杂信息处理中的一种选择性损伤 在相同的域中节省更简单的信息处理，以及 不涉及视觉空间域。这样做的目的是 项目有：1)定义受损和完好的能力 在神经心理学领域内和跨领域 在自闭症中的功能和定义的质量特征 这些缺陷是自闭症特有的，与 精神发育迟滞对这些基因表达的影响 赤字；2)解决有关 神经心理缺陷与完全性的特点 自闭症的能力，并提供证据表明几种替代方案 不支持对这一模式提出的解释；以及3) 确定受试者使用的具体策略或方法 用于任务绩效。项目I的目标将是 通过以下管理完成：1)一组 评估一系列能力的神经心理测试 跨域，在辅助和视觉两种形态中 (组成部分1)；2)选定的神经心理学程序 进一步描述缺陷和完整的能力，解决问题的关键 关于它们的性质的悬而未决的问题，并进行调查 建议替代赤字以解释#年的赤字模式 自闭症(第二部分)；和3)实验认知过程 它提供了对高管的详细认知分析， 在任务执行中使用的分析、模式分析能力 (组件3)。组件的神经心理操作 1将服务于更广泛的目的，即为 项目II和项目III中对临床表达的研究 自闭症的缺陷和更广泛的缺陷模式。

Numerous neurobehavioral models have been proposed to account for the clinical manifestations of autism. Our research examining neuropsychologic function across domains modalities has provided evidence of concurrent impairments in higher order abilities across domains, intact simpler abilities in these same domains, and the integrity of basic information acquisition abilities. Based on the dissociation between simple and complex abilities within domains and the predominance of clinical impairments in domains with the highest demands for complex information processing, we have proposed that autism is the consequence of a selective impairment in complex information processing that spares simpler information processing in the same domains, and does not involve the visual-spatial domain. The goals of this project are: 1) to define the impaired and intact abilities within and across domains that characterize neuropsychologic functioning in autism and ot define the qualitative features of the deficits that are specific to autism and independent of the influence of mental retardation on the expression of these deficits; 2) to address key unanswered questions about the neutropsychologic characteristics of the deficits and intact abilities in autism and provide evidence that several alternative explanations proposed for this pattern are not supported; and 3) to determine the specific strategies or methods used by subjects for task performance. Thje goals of Project I will be accomplished through the administration of: 1) a battery of neuropsychologic tests that assess a range of abilities within and across domains and in both the autitory and visual modalities (Component 1); 2) selected neuropsychologic procedures that further characterize deficits and intact abilities, address key unresolved questions about their nature, and investigate alternative deficits proposed to explain the deficit pattern in autism (Component 2); and 3) experimental cognitive procedures that provide a detailed cognitive analysis of executive, analytic, and pattern analysis abilities used in task performance (Component 3). The neuropyschologic procedures from Component 1 will serve a broader purpose of providing a common linkfor studies in Projects II and III to the clinical expression of the deficits and to the broader pattern of deficits in autism.