EFFECTS OF FASTING ON PULSATILE GH AND LH SECRETION IN MEN AND WOMEN

禁食对男性和女性脉动 GH 和 LH 分泌的影响

• 批准号: 6307469
• 负责人: JOHANNES D VELDHUIS
• 金额: $ 2.81万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2001-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6307469
• 关键词: estradiol; fasting; hormone biosynthesis; hormone regulation /control mechanism; human subject; luteinizing hormone; somatotropin

The stress-related suppressive effect of fasting on the human gonadotropic (LH) axis is augmented by the negative feedback action of estradiol. This thesis will be tested by applying placebo versus estradiol-impregnated skin patches on a fasted and fed day in healthy adults and observing the negative feedback action of this naturally occurring steroid in the two nutritional environments. GH will be measured as a control hormone.

应激相关的禁食对人促性腺激素（LH）轴的抑制作用被雌二醇的负反馈作用增强。 本论文将通过在健康成年人禁食和进食日应用安慰剂与雌二醇浸渍的皮肤贴剂进行测试，并观察这种天然类固醇在两种营养环境中的负反馈作用。 将测量GH作为对照激素。