ACCURACY OF HIGH-RESOLUTION MULTI-SHOT DWI FOR THE DETECTION OF BREAST CANCER

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 弥散加权成像（DWI）可以提供与微血管变化无关的信息， 对比增强MRI -可以提高MRI诊断乳腺癌的特异性。迄今为止， 从DWI可能提供的信息内容来看，由于使用单次激发技术， 对几何失真的敏感性和检测到的病变尺寸的限制。这个符合HIPAA标准，IRB批准的 本研究旨在比较乳腺高分辨率DWI与“常规”动态对比的敏感性和特异性 增强核磁共振成像和病理学 要了解卢卡斯中心正在进行的其他项目，请访问http://rsl.stanford.edu/ （卢卡斯年度报告和 ISMRM 2011摘要）

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Diffusion-weighted imaging (DWI) may provide information - physically unrelated to microvascular changes detected by contrast-enhanced MRI - that can improve the specificity of MRI for breast cancer diagnosis. Attempts thus far to benefit from the information content that DWI may offer have been limited by the use of single-shot techniques, with inherent sensitivity to geometric distortions and limitations in detected lesion size. The aim of this HIPAA-compliant, IRB-approved study was to compare the sensitivity and specificity of high-resolution DWI of the breast to 'conventional' dynamic-contrast enhanced MRI, and to pathology. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)