NOVEL PUMP FOR TIDAL FLOW EXTRACORPOREAL SUPPORT

描述（未编辑的申请人摘要）：使用萃取循环 在几种血液处理应用中，包括血液透析、呼吸 支持和血液加热/冷却。这些程序通常需要两个 血管穿刺部位;一个用于引流血液，另一个用于返回治疗 血血液处理应用也可以使用单个微处理器来执行。 在潮汐流布置中的套管，其交替地排出和输注 血的量。使用单个套管系统具有相当大的成本， 安全性优于当前的双套管系统。巴克斯特MetaPlus泵 具有安全功能，使其成为唯一的商用泵 适合于在单个套管、潮汐流构造中使用。潮汐流 体外血液泵（T型泵）将以 辅助电子控制器和夹具组件， 与MetaPlus泵配合使用。一种新的夹具配置和流程 将采用控制算法来提高安全性和有效性，并允许 该系统适应患者血流/压力条件的变化。相 II研究将包括控制软件的完善，控制器的设计 控制台，改良夹钳设计，广泛的体内评价，以及 系统的包装。 拟定商业应用： 不可用

DESCRIPTION (Unedited Applicant's Abstract):Extracorporeal Circulation is used in several blood treatment applications, including hemodialysis, respiratory support, and blood warming/cooling. These procedures usually require two vascular access sites; one for draining blood and the other returning treated blood. The blood treatment applications can also be performed using a single cannula in a tidal flow arrangement that alternately drains and infuses a volume of blood. The use of a single cannula system has considerable cost and safety advantages over the current two-cannula system. The Baxter MetaPlus Pump possesses safety features that make it the only commercially available pump suitable for use in a single cannula, tidal flow configuration. A tidal flow extracorporeal blood pump (T-Pump) will be developed in the form of an auxiliary electronic controller and clamp assembly designed to be used in conjunction with the MetaPlus pump. A novel clamp configuration and flow control algorithm will be employed to increase safety and efficacy, and allow the system to adapt to changes in patient blood flow/pressure conditions. Phase II research will include refinement of control software, design of a control console, modification of clamp design, extensive evaluation in vivo, and packaging of the system. PROPOSED COMMERCIAL APPLICATION: Not Available