ENERGY RESOLVED DIGITAL HPGE X OR Y-RAY IMAGING DETECTOR

用于10至150 keV光子的成像探测器在医疗技术中有许多用途，包括肿瘤成像，SPECT和放射照相。数字输出尤其有用，因为它允许图像增强、分析、传输和存储。在第一阶段，我们提出了一种新技术，可以捕获100微米空间分辨率和1 keV能量分辨率或更高的图像。这种能力将促进全新种类的医疗诊断程序，特别是转基因小动物成像。我们第一阶段的工作证明了这种方法的可行性。在第二阶段的工作中，我们将与LBNL的Paul Luke合作，构建1厘米厚的交叉带HPGe探测器，具有10 x 10条，每条2 mm x 20 mm。我们将开发这种方法特别要求的具有低噪声和大带宽特性的冷却场效应管前置放大器。我们还将开发模拟滤波电子设备来调节探测器的新信号，并采用数字脉冲处理电子设备以高达10/6 cps的速率获取这些信号。最后，我们将设计程序来测试检测器的线性度，并开发处理算法来完善这种质量。第二阶段将以工作和测试原型结束。第三阶段将主要涉及生产工程方面的工作。建议的商业应用：作为一种100微米空间分辨率的能量分辨率数字探测器，建议的探测器技术可以找到许多医疗应用，包括SPECT，小型哺乳动物的能量分辨率血管造影，啮齿动物骨骼的骨密度测定，以及小型手持伽马相机。非医疗应用将包括无损检测、天体物理伽马成像、核清理用途和x射线衍射探测器。

Imaging detectors for 10 to 150 keV photons have many uses in medical technology, including tumor imaging, SPECT, and radiography. Digital output is particularly useful since it allows image enhancement, analysis, transmission and storage. In Phase I we proposed a new technology that could capture images with 100 microm spatial resolution and 1 keV energy resolution or better. This capability would facilitate entirely new classes of medical diagnostic procedures, particularly for transgenic small animal imaging. Our Phase I work demonstrated the feasibility of this approach. In this Phase II effort, collaborating with Paul Luke at LBNL, we will construct 1 cm thick crossed-strip HPGe detectors having 10 x 10 strips, each 2 mm x 20 mm. We will develop cooled FET preamplifiers having low noise and large bandwidth properties specifically required by this approach. We will also develop analog filtering electronics to condition the detector's novel signals and employ digital pulse processing electronics to acquire these signals at rates up to 10/6 cps. Finally, we will devise procedures to test the detector's linearity and develop processing algorithms to perfect this quality. Phase II will conclude with a working and tested prototype. Phase III will entail primarily production engineering efforts. PROPOSED COMMERCIAL APPLICATION: As an energy resolved digital detector with 100 microm spatial resolution, the proposed detector technology could find many medical applications, including SPECT, energy resolved angiography for small mammals, bone densitometry on rodent bones, and small, hand-held gamma cameras. Non-medical applications would include non-destructive testing, astrophysical gamma imaging, nuclear cleanup uses, and x-ray diffraction detectors.