A new strategy for treating demyelinating diseases

治疗脱髓鞘疾病的新策略

• 批准号: nhmrc : GNT1058647
• 负责人: A/Pr Richard Hughes
• 金额: $ 32万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/new-strategy-treating-demyelinating-diseases/1344656
• 关键词: new; strategy; treating; demyelinating; diseases

Incomplete remyelination is a significant component of the persistent clinical disability of peripheral demyelinating neuropathy, contributing to conduction deficits and the secondary axonal damage. A crucial therapeutic challenge is to identify ways to promote remyelination. This project aims to develop a new strategy and a novel clinically relevant target for treating peripheral demyelinating neuropathy.

不完全的髓鞘再生是外周脱髓鞘神经病持续临床残疾的重要组成部分，导致传导缺陷和继发性轴突损伤。一个关键的治疗挑战是找出促进髓鞘再生的方法。该项目旨在开发一种新的治疗外周脱髓鞘神经病的新策略和新的临床相关靶点。