FIELD STUDY OF SMOKING CESSATION IN ALCOHOLISM TREATMENT

酗酒治疗中戒烟的实地研究

• 批准号: 6168339
• 负责人: NED L COONEY
• 金额: $ 26.83万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2002-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6168339
• 关键词: alcoholism /alcohol abuse; alcoholism /alcohol abuse therapy; behavioral /social science research tag; clinical research; coping; craving; epidemiology; human subject; human therapy evaluation; interview; nicotine replacement; outcomes research; psychological tests; questionnaires; smoking cessation; transdermal drug delivery

APPLICANT'S ABSTRACT: This study was designed to increase understanding about the alcohol-tobacco interaction processes that impact the treatment of individuals with combined alcohol and nicotine dependence. Treatment outcome methodology will be combined with sophisticated Ecological Momentary Assessment methodology in order to examine the extent to which smoking serves as a cue for alcohol craving and/or a response to alcohol craving in treated alcoholics. A secondary aim of the study will be to examine treatment outcome effects of delivering a smoking cessation intervention concurrent with ambulatory treatment for alcohol dependence. If smoking cessation treatment is found to affect alcohol outcome, further analyses will be conducted to determine the impact of possible mediators of this effect such as alcohol abstinence self-efficacy and alcohol-related coping skills. Subjects will be 112 alcoholics who have requested alcohol treatment and are willing to attempt smoking cessation. Subjects will be veterans participating in the Substance Abuse Day Programs at the Newington and West Haven campuses of the VA Connecticut Healthcare System. Non-veteran women will be recruited from the community and enrolled in the Day Program to ensure adequate gender representation. One week after admission to the Day Program, subjects will be randomly assigned to one of the following two conditions: (1) Intensive smoking cessation therapy (behavioral counseling plus nicotine replacement using nicotine patches) concurrent with alcohol treatment, or (2) Brief smoking cessation advice concurrent with alcohol treatment. Two days before completing the Day Program, subjects will be instructed in self-monitoring of moods, situations, drinking, smoking and urges to drink or smoke using a hand-held computer that will beep them for assessment at random times 4 times/day. They will also be instructed to activate the computer immediately prior to, and just following, smoking each of four cigarettes per day. After leaving treatment they will continue to self-monitor for 14 days. Outcome will be measured at 14 days, three months and six months posttreatment using interviews, questionnaires, and biological measures.

申请人摘要：这项研究旨在增加对 关于酒精和烟草的相互作用过程， 酒精和尼古丁依赖的人。 治疗 结果方法将与复杂的生态瞬间相结合 评估方法，以检查吸烟对健康的影响程度 作为酒精渴望的线索和/或对酒精渴望的反应， 治疗酗酒者。 研究的第二个目的是检查 实施戒烟干预的治疗效果 同时进行酒精依赖门诊治疗。 如果吸烟 发现戒酒治疗影响酒精结果，进一步分析 将进行，以确定可能的调解人的影响， 戒酒自我效能和酒精应对等影响 skills. 受试者将是112名要求饮酒的酗酒者 治疗，并愿意尝试戒烟。 受试者将 参加纽因顿药物滥用日项目的退伍军人 和弗吉尼亚州康涅狄格州医疗保健系统的西黑文校区。 非退伍军人妇女将从社区招募， 确保适当性别代表性的日间方案。 后一周 入读日间课程后，受试者将被随机分配至 以下两种情况：（1）强化戒烟治疗 （行为咨询加尼古丁贴片尼古丁替代） 与酒精治疗同时进行，或（2）简短的戒烟建议 同时进行酒精治疗。 完成日前两天 受试者将被指导自我监测情绪， 情况下，饮酒，吸烟和冲动喝酒或吸烟使用手持 计算机将哔哔他们在随机时间评估4次/天。 他们还将被指示在即将启动计算机之前， 然后每天抽四支烟 离开 他们将继续自我监测14天。 结果将是 在治疗后14天、3个月和6个月使用 访谈、问卷调查和生物测量。