REGULATION OF METABOLISM IN PARASITIC HELMINTHS

寄生蠕虫代谢的调节

• 批准号: 6373101
• 负责人: Ben Gerald Harris
• 金额: $ 24.66万
• 依托单位: UNIVERSITY OF NORTH TEXAS HLTH SCI CTR
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-04-01 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6373101
• 关键词: 6 phosphofructokinase; Ascaris; Nematoda; bioenergetics; carbohydrate metabolism; circular dichroism; enzyme activity; enzyme mechanism; enzyme substrate; glycolysis; high performance liquid chromatography; host organism interaction; nucleic acid sequence; phosphorylation; protein kinase; protein structure function; proteolysis

DESCRIPTION (Adapted from the Applicant's Abstract): The overall objective of this research program is to develop a clear understanding of carbohydrate metabolism in parasitic helminths. Inherent in this objective is the delineation of the regulatory steps which control the flow of carbon through this pathway. A complete description of these regulatory steps and their modulators would provide unique information on the parasite and the manner in which it relates to its environment, the host.

描述（改编自申请人的摘要）： 这项研究计划是为了对碳水化合物有一个清晰的认识， 寄生蠕虫的新陈代谢。这一目标所固有的是， 划定控制碳流动的监管步骤， 这条路。对这些监管步骤及其 调节剂将提供关于寄生虫的独特信息， 它与它所处的环境，宿主，