A prospective study of the development of innate immunity in preterm infants and susceptibility to neonatal infection

早产儿先天免疫发育和新生儿感染易感性的前瞻性研究

• 批准号: nhmrc : 572548
• 负责人: A/Pr Ofer Levy
• 金额: $ 25.19万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prospective-study-development-neonatal-infection/80929
• 关键词: prospective; study; development; innate; immunity

Life-threatening infection is extremely common in preterm infants, affecting at least 25% of those born before 28 weeks. Infection results in huge human and economic costs. There is currently no way of predicting which preterm infants will develop infection. This project will enrol preterm infants at birth and track the development of their protective immune system over the period of greatest vulnerability. This will lead to development of targeted treatement for those at greatest risk.

危及生命的感染在早产儿中极为常见，影响至少 25% 28 周前出生的早产儿。感染会造成巨大的人力和经济损失。目前无法预测哪些早产儿会感染。该项目将招募出生时的早产儿，并跟踪他们在最脆弱时期保护性免疫系统的发育情况。这将导致为风险最大的人开发有针对性的治疗方法。