BIOMED RES FACIL: SPINAL CORD INJ

Biomed RES FACIL：脊髓注射

• 批准号: 6794392
• 负责人: DENNIS D CUNNINGHAM
• 金额: $ 39.3万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-17 至 2003-06-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794392
• 关键词: Rodentias; behavior test; biomedical facility; building /facility design /renovation; communicable diseases; immunology; neoplasm /cancer genetics; neurosciences; spinal cord; spinal cord injury; university

DESCRIPTION (provided by applicant): This application proposes construction of the Procedural and Behavioral Housing Suites (PBHS), a 5,215 sq. ft. vivarium expansion in the BRC at the UC- Irvine College of Medicine. Partially completed and under phased construction, the BRC is planned as a four building, 200,000 sq. ft. complex dedicated to interdisciplinary research in the areas of neuroscience, cancer, genetics, immunology, and infectious disease. Biomedical research by current faculty and those under recruitment relies heavily on animal research, creating an urgent need to increase vivarium space for PBHS. The project would expand the existing 12,320 sq. ft. Gillespie Vivarium and connect the underground vivarium complex to the four BRC buildings (one operational, two under construction, and one planned). The PBHS would consist of three suites, each efficiently combining rooms of three basic types: 1) procedure rooms; 2) behavioral testing rooms; and 3) rodent holding rooms. The construction also would include a smaller three-room Gillespie Vivarium Extension (one housing room, one behavioral testing room, and an anteroom). The procedure and behavioral testing rooms have been designed to allow conversion into animal housing or a different mix of testing and procedure rooms. There is an architectural option to convert one or more of the suites into barrier facilities if need arises. Temporary procedure and testing rooms would be released to revert to their original purpose of animal housing. The application identifies a group of PHS-funded faculty members who would use the PBHS to advance biomedical knowledge in areas important to the nation's health.

描述（由申请人提供）：本申请提议在加州大学欧文分校医学院的 BRC 内建造程序和行为住房套房 (PBHS)，这是一个 5,215 平方英尺的动物园扩建项目。 BRC 已部分完工，正在分阶段建设中，规划为一座占地 200,000 平方英尺的四栋大楼，致力于神经科学、癌症、遗传学、免疫学和传染病领域的跨学科研究。现有教师和正在招聘的教师的生物医学研究在很大程度上依赖于动物研究，因此迫切需要增加 PBHS 的饲养空间。该项目将扩建现有的 12,320 平方英尺的 Gillespie 动物园，并将地下动物园综合体与四栋 BRC 建筑（一栋正在运营，两栋在建，一栋规划）连接起来。 PBHS​​ 将由三间套房组成，每间套房有效地结合了三种基本类型的房间：1）手术室； 2）行为测试室； 3) 啮齿动物收容室。该建筑还将包括一个较小的三室吉莱斯皮动物园扩建项目（一间住房室、一间行为测试室和一间接待室）。程序和行为测试室的设计允许转换为动物房屋或不同的测试和程序室组合。如果需要，可以选择将其中一间或多间套房改造成屏障设施。临时程序和测试室将被释放，恢复其最初的动物饲养用途。该申请确定了一组由 PHS 资助的教职人员，他们将利用 PBHS 来推进对国家健康重要领域的生物医学知识。