PURCHASE OF VENTILATED MOUSE CAGES

购买通风鼠笼

• 批准号: 6600790
• 负责人: DENNIS D CUNNINGHAM
• 金额: $ 64.87万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-02-01 至 2004-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6600790
• 关键词: animal care; animal colony; biomedical equipment purchase; laboratory mouse

DESCRIPTION (provided by applicant): This animal resource improvement project proposes to purchase ventilated mouse cages for two National Center for Research Resources (NCRR)-funded construction projects: the Genetically Modified Rodent Facility (GMRF) and the Procedural and Behavioral Housing Suites (PBHS). The GMRF has received NCRR approval for both the schematic and development design phases, has submitted design Phase III construction documents, and is scheduled to begin construction on July 1, 2002 (completion November 2002). The PBHS project received a notice of intent to award and, pending funding and design review, should begin construction by July 2003 (completion March 2004). The short-term goal of this project is to address an immediate and serious shortfall in mouse housing for ongoing biomedical research by UCI faculty. In particular, the use of genetically modified mice by UCI researchers has increased by an average of 28 percent per year during the past six years. The GMRF is designed to accommodate 3,150 ventilated mouse cage and; the PBHS 1,926 mouse cages. The long-term goal of the centrally administered University Laboratory Animal Resources (ULAR) is to develop animal housing at a pace that matches intensive laboratory construction and faculty recruitment; the campus will invest $5 to $6 million in caging alone over the next five years. Connected to the improved animal resource are two 50,000 sq. ft. laboratory buildings, Sprague and Hewitt Hall, scheduled to open in 2002 and 2003, respectively. Based on current usage, approximately half of the requested caging capacity will be filled immediately, with the remainder fully utilized by rapid projected growth in two years. The 1,926 cages for the PBHS will be purchased and installed to coordinate with the completion of the PBHS. Ventilated cage racks were integrated into the design proposals for both GMRF and PBHS in order to increase housing density, leverage valuable barrier space, maximize integrated behavior and procedure research, and help protect sensitive and valuable rodent stocks.

描述(由申请人提供)： 这个动物资源改进项目计划为两个由国家研究资源中心(NCRR)资助的建设项目购买通风鼠笼：转基因啮齿动物设施(GMRF)和程序和行为住房套房(PBHS)。GMRF已获得NCRR对原理图和开发设计阶段的批准，已提交设计第三阶段施工文件，并计划于2002年7月1日开始施工(2002年11月竣工)。PBHS项目收到了授标意向通知，在等待资金和设计审查期间，应于2003年7月开始施工(2004年3月竣工)。该项目的短期目标是解决加州大学学院教职员工正在进行的生物医学研究中老鼠住所的直接和严重短缺问题。特别是，在过去的六年中，UCI研究人员使用转基因小鼠的数量平均每年增加28%。GMRF的设计可容纳3,150个通风鼠笼和PBHS 1,926个鼠笼。中央管理的大学实验动物资源中心(ULAR)的长期目标是以与密集的实验室建设和教师招聘相匹配的速度发展动物收容所；该园区将在未来五年内仅在笼养方面投资500至600万美元。与改良的动物资源相连的是两个50,000平方英尺的动物。英国《金融时报》实验室大楼，斯普拉格和休伊特大厅，计划分别于2002年和2003年开放。根据目前的使用量，大约一半的请求笼子容量将立即填满，其余的将在两年内快速增长时全部使用。当局会为该计划购买和安装1,926个机笼，以配合该计划的落成。通风笼架被整合到GMRF和PBHS的设计方案中，以增加住房密度，利用宝贵的屏障空间，最大限度地进行综合行为和程序研究，并帮助保护敏感和有价值的啮齿动物种群。