CELL GROWTH & APOPTOSIS, PERIDONTAL DIS

描述(申请人提供)：VCU提出了一个改造项目，将改造10,974平方米。英国《金融时报》位于桑格大厅(一栋有40年历史的医学大楼)二楼的陈旧的办公和实验室空间，变成了一个细胞和分子信号设施，用于合作研究和培训。具体来说，翻修后的空间将容纳首席调查员(PI)，研究导致癌症、心血管和神经系统功能障碍、糖尿病、炎症性疾病和药物滥用的细胞信号过程。因此，该设施将联合和集中这些研究人员，并将作为新的合作和研究努力的环境催化剂。这反过来将导致知识共享和新的筹资倡议，这将导致新的进步和发现。这项申请的动机有两个：1)目前的实验室设施陈旧、受限，不足以支持目前得到资助的研究；2)缺乏足够的设施，阻碍了招聘强大的以研究为导向的教师和研究生。新设计的实验室空间将提供：促进同事之间合作的开放式设计，为个人主管和研究生提供的计算机和办公桌空间，以及共享设备和实施现代技术的专门区域。一旦完工，翻新后的空间不仅将增强VCU研究人员开展目前获得资助的项目的能力，还将提高未来获得资金的可能性。这项应用的长期目标是提供新的基础设施，以促进在细胞和分子信号领域建立国家公认的专业中心的发展。

DESCRIPTION (provided by applicant): The VCU proposes a renovation project that will transform 10,974 sq. ft. of outdated office and laboratory space, located on the second floor of Sanger Hall (a 40-year-old medical sciences building) into a Cellular and Molecular Signaling Facility for collaborative research and training. Specifically, the renovated space will house Principal Investigators (PIs) studying cellular signaling processes that contribute to: cancer, cardiovascular and nervous system dysfunction, diabetes, inflammatory diseases, and substance abuse. Thus, this facility will unite and centralize these researchers, and will serve as an environmental catalyst for new collaborations and research efforts. This in turn will lead to knowledge sharing and new funding initiatives, which will result in new advances and discoveries. The motivation for this application is two-fold: 1) the current laboratory facilities are outdated, confined, and inadequate for currently funded research; and 2) recruiting strong research-oriented faculty and graduate students is hindered by lack of adequate facilities. The newly designed laboratory space will offer: an open design to promote collaboration among co-workers, computer and desk space for PIs and graduate students, and specialized areas for equipment sharing and implementation of modern techniques. Once completed, the renovated space will not only enhance the ability of VCU researchers to conduct currently funded projects, but will also improve the likelihood of future funding. The long-term objective of this application is to provide new infrastructure that will stimulate the development of a nationally recognized center of expertise in the field of cellular and molecular signaling.