CELL GROWTH & APOPTOSIS, CANCER

细胞生长

• 批准号: 6794403
• 负责人: MARSHA R TORR
• 金额: $ 49.88万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2003-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794403
• 关键词: apoptosis; biological signal transduction; biomedical facility; building /facility design /renovation; cell cycle; neoplasm /cancer; pathologic process; training

DESCRIPTION (provided by applicant): The VCU proposes a renovation project that will transform 10,974 sq. ft. of outdated office and laboratory space, located on the second floor of Sanger Hall (a 40-year-old medical sciences building) into a Cellular and Molecular Signaling Facility for collaborative research and training. Specifically, the renovated space will house Principal Investigators (PIs) studying cellular signaling processes that contribute to: cancer, cardiovascular and nervous system dysfunction, diabetes, inflammatory diseases, and substance abuse. Thus, this facility will unite and centralize these researchers, and will serve as an environmental catalyst for new collaborations and research efforts. This in turn will lead to knowledge sharing and new funding initiatives, which will result in new advances and discoveries. The motivation for this application is two-fold: 1) the current laboratory facilities are outdated, confined, and inadequate for currently funded research; and 2) recruiting strong research-oriented faculty and graduate students is hindered by lack of adequate facilities. The newly designed laboratory space will offer: an open design to promote collaboration among co-workers, computer and desk space for PIs and graduate students, and specialized areas for equipment sharing and implementation of modern techniques. Once completed, the renovated space will not only enhance the ability of VCU researchers to conduct currently funded projects, but will also improve the likelihood of future funding. The long-term objective of this application is to provide new infrastructure that will stimulate the development of a nationally recognized center of expertise in the field of cellular and molecular signaling.

描述（由申请人提供）：VCU提出了一个改造项目，将改造10,974平方米。将位于桑格大厅（一座有40年历史的医学大楼）二楼的过时的办公室和实验室空间改造成一个细胞和分子信号设施，用于合作研究和培训。具体来说，翻修后的空间将容纳主要研究人员（pi）研究细胞信号传导过程，这些过程有助于：癌症、心血管和神经系统功能障碍、糖尿病、炎症性疾病和药物滥用。因此，该设施将联合和集中这些研究人员，并将作为新的合作和研究努力的环境催化剂。这反过来将导致知识共享和新的资助倡议，从而带来新的进展和发现。这一申请的动机是双重的：1)目前的实验室设施已经过时，局限，并且不适合目前资助的研究；2)由于缺乏足够的设施，招收强大的研究型教师和研究生受到阻碍。新设计的实验室空间将提供：一个开放的设计，以促进同事之间的协作，为pi和研究生提供计算机和办公桌空间，以及用于设备共享和现代技术实施的专门区域。一旦完成，改造后的空间不仅将提高VCU研究人员进行当前资助项目的能力，而且还将提高未来资助的可能性。这项申请的长期目标是提供新的基础设施，以促进全国公认的细胞和分子信号领域专业知识中心的发展。